{"id":8321,"date":"2026-02-28T17:31:39","date_gmt":"2026-02-28T13:31:39","guid":{"rendered":"https:\/\/gastroclinic.am\/?p=8321"},"modified":"2026-02-28T17:38:28","modified_gmt":"2026-02-28T13:38:28","slug":"ozempic","status":"publish","type":"post","link":"https:\/\/gastroclinic.am\/en\/ozempic\/","title":{"rendered":"Ozempic: contraindications and effectiveness"},"content":{"rendered":"\n\t<div id=\"text-2165856675\" class=\"text\">\n\t\t\n\n<h2 data-start=\"4124\" data-end=\"4143\">What is Ozempic?<\/h2>\n<p data-start=\"4145\" data-end=\"4277\"><a href=\"https:\/\/www.ozempic.com\/\">Ozempic\u00ae (semaglutide)<\/a> is a GLP-1 (glucagon-like peptide-1) receptor agonist approved for the treatment of type 2 diabetes mellitus.<\/p>\n<p data-start=\"4279\" data-end=\"4368\">A separate formulation of semaglutide <a href=\"https:\/\/www.wegovy.com\/\">(Wegovy\u00ae)<\/a> is approved for the treatment of obesity.<\/p>\n<p data-start=\"4370\" data-end=\"4428\">The medication is administered subcutaneously once weekly.<\/p>\n<hr data-start=\"4430\" data-end=\"4433\" \/>\n<h2 data-start=\"4435\" data-end=\"4457\">Mechanism of Action<\/h2>\n<p data-start=\"4459\" data-end=\"4471\">Semaglutide:<\/p>\n<ul data-start=\"4473\" data-end=\"4654\">\n<li data-start=\"4473\" data-end=\"4520\">\n<p data-start=\"4475\" data-end=\"4520\">enhances glucose-dependent insulin secretion;<\/p>\n<\/li>\n<li data-start=\"4521\" data-end=\"4550\">\n<p data-start=\"4523\" data-end=\"4550\">reduces glucagon secretion;<\/p>\n<\/li>\n<li data-start=\"4551\" data-end=\"4577\">\n<p data-start=\"4553\" data-end=\"4577\">delays gastric emptying;<\/p>\n<\/li>\n<li data-start=\"4578\" data-end=\"4630\">\n<p data-start=\"4580\" data-end=\"4630\">decreases appetite via central satiety mechanisms;<\/p>\n<\/li>\n<li data-start=\"4631\" data-end=\"4654\">\n<p data-start=\"4633\" data-end=\"4654\">promotes weight loss.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"4656\" data-end=\"4733\">The delay in gastric emptying explains most gastrointestinal adverse effects.<\/p>\n<hr data-start=\"4735\" data-end=\"4738\" \/>\n<h2 data-start=\"4740\" data-end=\"4754\">Indications<\/h2>\n<h3 data-start=\"4756\" data-end=\"4806\">Ozempic (according to prescribing information)<\/h3>\n<p data-start=\"4808\" data-end=\"4824\">Type 2 diabetes:<\/p>\n<ul data-start=\"4825\" data-end=\"4953\">\n<li data-start=\"4825\" data-end=\"4855\">\n<p data-start=\"4827\" data-end=\"4855\">inadequate glycemic control;<\/p>\n<\/li>\n<li data-start=\"4856\" data-end=\"4908\">\n<p data-start=\"4858\" data-end=\"4908\">in combination with other glucose-lowering agents;<\/p>\n<\/li>\n<li data-start=\"4909\" data-end=\"4953\">\n<p data-start=\"4911\" data-end=\"4953\">in patients with high cardiovascular risk.<\/p>\n<\/li>\n<\/ul>\n<h3 data-start=\"4955\" data-end=\"4991\">Semaglutide for obesity (Wegovy)<\/h3>\n<ul data-start=\"4993\" data-end=\"5090\">\n<li data-start=\"4993\" data-end=\"5016\">\n<p data-start=\"4995\" data-end=\"5016\">BMI \u2265 30 kg\/m\u00b2<br data-start=\"5009\" data-end=\"5012\" \/>or<\/p>\n<\/li>\n<li data-start=\"5017\" data-end=\"5090\">\n<p data-start=\"5019\" data-end=\"5090\">BMI \u2265 27 kg\/m\u00b2 + metabolic comorbidities (diabetes, hypertension, etc.)<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"5092\" data-end=\"5095\" \/>\n<h2 data-start=\"5097\" data-end=\"5115\">Proven Efficacy<\/h2>\n<h3 data-start=\"5117\" data-end=\"5137\">Glycemic Control<\/h3>\n<p data-start=\"5139\" data-end=\"5167\">According to SUSTAIN trials:<\/p>\n<ul data-start=\"5168\" data-end=\"5261\">\n<li data-start=\"5168\" data-end=\"5201\">\n<p data-start=\"5170\" data-end=\"5201\">significant reduction in HbA1c;<\/p>\n<\/li>\n<li data-start=\"5202\" data-end=\"5261\">\n<p data-start=\"5204\" data-end=\"5261\">reduction in cardiovascular events in high-risk patients.<\/p>\n<\/li>\n<\/ul>\n<h3 data-start=\"5263\" data-end=\"5278\">Weight Loss<\/h3>\n<p data-start=\"5280\" data-end=\"5295\">In STEP trials:<\/p>\n<ul data-start=\"5296\" data-end=\"5437\">\n<li data-start=\"5296\" data-end=\"5352\">\n<p data-start=\"5298\" data-end=\"5352\">average weight reduction of ~15% at therapeutic doses;<\/p>\n<\/li>\n<li data-start=\"5353\" data-end=\"5390\">\n<p data-start=\"5355\" data-end=\"5390\">effect maintained during treatment;<\/p>\n<\/li>\n<li data-start=\"5391\" data-end=\"5437\">\n<p data-start=\"5393\" data-end=\"5437\">partial weight regain after discontinuation.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"5439\" data-end=\"5442\" \/>\n<h2 data-start=\"5444\" data-end=\"5459\">Side Effects<\/h2>\n<p data-start=\"5461\" data-end=\"5500\">Most common (especially at initiation):<\/p>\n<ul data-start=\"5502\" data-end=\"5586\">\n<li data-start=\"5502\" data-end=\"5510\">\n<p data-start=\"5504\" data-end=\"5510\">nausea<\/p>\n<\/li>\n<li data-start=\"5511\" data-end=\"5521\">\n<p data-start=\"5513\" data-end=\"5521\">vomiting<\/p>\n<\/li>\n<li data-start=\"5522\" data-end=\"5532\">\n<p data-start=\"5524\" data-end=\"5532\">bloating<\/p>\n<\/li>\n<li data-start=\"5533\" data-end=\"5547\">\n<p data-start=\"5535\" data-end=\"5547\">constipation<\/p>\n<\/li>\n<li data-start=\"5548\" data-end=\"5558\">\n<p data-start=\"5550\" data-end=\"5558\">diarrhea<\/p>\n<\/li>\n<li data-start=\"5559\" data-end=\"5570\">\n<p data-start=\"5561\" data-end=\"5570\">heartburn<\/p>\n<\/li>\n<li data-start=\"5571\" data-end=\"5586\">\n<p data-start=\"5573\" data-end=\"5586\">early satiety<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"5588\" data-end=\"5600\">Less common:<\/p>\n<ul data-start=\"5602\" data-end=\"5719\">\n<li data-start=\"5602\" data-end=\"5617\">\n<p data-start=\"5604\" data-end=\"5617\">gastroparesis<\/p>\n<\/li>\n<li data-start=\"5618\" data-end=\"5660\">\n<p data-start=\"5620\" data-end=\"5660\">pancreatitis (rare; association debated)<\/p>\n<\/li>\n<li data-start=\"5661\" data-end=\"5719\">\n<p data-start=\"5663\" data-end=\"5719\">gallstone disease (more frequent with rapid weight loss)<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"5721\" data-end=\"5746\">Most adverse effects are:<\/p>\n<ul data-start=\"5747\" data-end=\"5803\">\n<li data-start=\"5747\" data-end=\"5764\">\n<p data-start=\"5749\" data-end=\"5764\">dose-dependent;<\/p>\n<\/li>\n<li data-start=\"5765\" data-end=\"5803\">\n<p data-start=\"5767\" data-end=\"5803\">reduced with gradual dose titration.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"5805\" data-end=\"5808\" \/>\n<h2 data-start=\"5810\" data-end=\"5830\">Contraindications<\/h2>\n<ul data-start=\"5832\" data-end=\"5980\">\n<li data-start=\"5832\" data-end=\"5881\">\n<p data-start=\"5834\" data-end=\"5881\">Medullary thyroid carcinoma (or family history)<\/p>\n<\/li>\n<li data-start=\"5882\" data-end=\"5926\">\n<p data-start=\"5884\" data-end=\"5926\">Multiple endocrine neoplasia type 2 (MEN2)<\/p>\n<\/li>\n<li data-start=\"5927\" data-end=\"5938\">\n<p data-start=\"5929\" data-end=\"5938\">Pregnancy<\/p>\n<\/li>\n<li data-start=\"5939\" data-end=\"5961\">\n<p data-start=\"5941\" data-end=\"5961\">Severe gastroparesis<\/p>\n<\/li>\n<li data-start=\"5962\" data-end=\"5980\">\n<p data-start=\"5964\" data-end=\"5980\">Hypersensitivity<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"5982\" data-end=\"6002\">Use with caution in:<\/p>\n<ul data-start=\"6003\" data-end=\"6065\">\n<li data-start=\"6003\" data-end=\"6025\">\n<p data-start=\"6005\" data-end=\"6025\">chronic pancreatitis<\/p>\n<\/li>\n<li data-start=\"6026\" data-end=\"6065\">\n<p data-start=\"6028\" data-end=\"6065\">significant gastrointestinal symptoms<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"6067\" data-end=\"6070\" \/>\n<h2 data-start=\"6072\" data-end=\"6115\">Semaglutide and Gastrointestinal Effects<\/h2>\n<p data-start=\"6117\" data-end=\"6153\">From a gastroenterology perspective:<\/p>\n<ul data-start=\"6155\" data-end=\"6354\">\n<li data-start=\"6155\" data-end=\"6203\">\n<p data-start=\"6157\" data-end=\"6203\">delayed gastric emptying may worsen dyspepsia;<\/p>\n<\/li>\n<li data-start=\"6204\" data-end=\"6236\">\n<p data-start=\"6206\" data-end=\"6236\">possible exacerbation of <a href=\"https:\/\/gastroclinic.am\/en\/gerd\/\">GERD<\/a>;<\/p>\n<\/li>\n<li data-start=\"6237\" data-end=\"6296\">\n<p data-start=\"6239\" data-end=\"6296\">possible worsening of IBS symptoms in sensitive patients;<\/p>\n<\/li>\n<li data-start=\"6297\" data-end=\"6354\">\n<p data-start=\"6299\" data-end=\"6354\">persistent severe nausea requires therapy reassessment.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"6356\" data-end=\"6440\">Prescription in patients with active GI complaints requires careful risk evaluation.<\/p>\n<hr data-start=\"6442\" data-end=\"6445\" \/>\n<h2 data-start=\"6447\" data-end=\"6488\">Can It Be Used \u201cJust for Weight Loss\u201d?<\/h2>\n<p data-start=\"6490\" data-end=\"6500\">Key point:<\/p>\n<p data-start=\"6502\" data-end=\"6551\">Semaglutide is a medication, not a cosmetic tool.<\/p>\n<p data-start=\"6553\" data-end=\"6580\">Prescription must consider:<\/p>\n<ul data-start=\"6582\" data-end=\"6650\">\n<li data-start=\"6582\" data-end=\"6588\">\n<p data-start=\"6584\" data-end=\"6588\">BMI;<\/p>\n<\/li>\n<li data-start=\"6589\" data-end=\"6609\">\n<p data-start=\"6591\" data-end=\"6609\">metabolic profile;<\/p>\n<\/li>\n<li data-start=\"6610\" data-end=\"6626\">\n<p data-start=\"6612\" data-end=\"6626\">comorbidities;<\/p>\n<\/li>\n<li data-start=\"6627\" data-end=\"6650\">\n<p data-start=\"6629\" data-end=\"6650\">risk\u2013benefit balance.<\/p>\n<\/li>\n<\/ul>\n<p data-start=\"6652\" data-end=\"6719\">Without lifestyle modification, long-term effectiveness is limited.<\/p>\n<hr data-start=\"6721\" data-end=\"6724\" \/>\n<h2 data-start=\"6726\" data-end=\"6755\">Frequently Asked Questions<\/h2>\n<h3 data-start=\"6757\" data-end=\"6802\">Does weight return after discontinuation?<\/h3>\n<p data-start=\"6804\" data-end=\"6869\">Yes, partially, if dietary and behavioral habits are not changed.<\/p>\n<h3 data-start=\"6871\" data-end=\"6904\">Is lifelong therapy required?<\/h3>\n<p data-start=\"6906\" data-end=\"6976\">The decision is individualized, as in any chronic metabolic condition.<\/p>\n<h3 data-start=\"6978\" data-end=\"7003\">Does it cause cancer?<\/h3>\n<p data-start=\"7005\" data-end=\"7137\">There is no evidence of increased cancer risk in humans. The warning relates to medullary thyroid carcinoma based on animal studies.<\/p>\n<hr data-start=\"7139\" data-end=\"7142\" \/>\n<h2 data-start=\"7144\" data-end=\"7167\">When to See a Doctor<\/h2>\n<ul data-start=\"7169\" data-end=\"7332\">\n<li data-start=\"7169\" data-end=\"7199\">\n<p data-start=\"7171\" data-end=\"7199\">presence of type 2 diabetes;<\/p>\n<\/li>\n<li data-start=\"7200\" data-end=\"7239\">\n<p data-start=\"7202\" data-end=\"7239\">obesity with metabolic complications;<\/p>\n<\/li>\n<li data-start=\"7240\" data-end=\"7279\">\n<p data-start=\"7242\" data-end=\"7279\">elevated ALT\/AST and suspected MASLD;<\/p>\n<\/li>\n<li data-start=\"7280\" data-end=\"7310\">\n<p data-start=\"7282\" data-end=\"7310\">significant GI side effects;<\/p>\n<\/li>\n<li data-start=\"7311\" data-end=\"7332\">\n<p data-start=\"7313\" data-end=\"7332\">pregnancy planning.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"7334\" data-end=\"7337\" \/>\n<h2 data-start=\"7339\" data-end=\"7352\">Conclusion<\/h2>\n<p data-start=\"7354\" data-end=\"7366\">Semaglutide:<\/p>\n<p data-start=\"7368\" data-end=\"7486\">\u2714 effective for diabetes and obesity management<br data-start=\"7415\" data-end=\"7418\" \/>\u2714 reduces cardiovascular risk<br data-start=\"7447\" data-end=\"7450\" \/>\u2714 leads to significant weight loss<\/p>\n<p data-start=\"7488\" data-end=\"7496\">However:<\/p>\n<p data-start=\"7498\" data-end=\"7612\">\u26a0 requires medical supervision<br data-start=\"7528\" data-end=\"7531\" \/>\u26a0 has gastrointestinal side effects<br data-start=\"7566\" data-end=\"7569\" \/>\u26a0 does not replace lifestyle modification<\/p>\n\t\t\n<style>\n#text-2165856675 {\n  font-size: 1rem;\n  line-height: 1;\n}\n<\/style>\n\t<\/div>\n\t\n<a data-animate=\"bounceIn\" class=\"button alert is-shade box-shadow-5-hover expand\" style=\"border-radius:99px;\">\n\t\t<span>ONLINE BOOKING<\/span>\n\t<i class=\"icon-angle-down\" aria-hidden=\"true\"><\/i><\/a>\n\n\n<div class=\"row row-small\"  id=\"row-1178318982\">\n\n\n\t<div id=\"col-828870439\" class=\"col medium-4 small-6 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\n    <div class=\"box has-hover has-hover box-default box-text-bottom\" >\n\n         <a href=\"https:\/\/gastroclinic.am\/en\/ourstaff\/irina-muradyan\/\" >         <div class=\"box-image \" >\n           <div class=\"box-image-inner image-cover\" style=\"border-radius:10%;padding-top:100%;\">\n              <img loading=\"lazy\" decoding=\"async\" width=\"1580\" height=\"1762\" src=\"https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/\u053b\u0580\u056b\u0576\u0561-\u0544\u0578\u0582\u0580\u0561\u0564\u0575\u0561\u0576-\u0567\u0576\u0564\u0578\u056f\u0580\u056b\u0576\u0578\u056c\u0578\u0563\u056b\u0561\u056f\u0561\u0576-\u056e\u0561\u057c\u0561\u0575\u0578\u0582\u0569\u0575\u0561\u0576-\u0572\u0565\u056f\u0561\u057e\u0561\u0580-1-scaled-e1764836080236.avif\" class=\"attachment- size- not-transparent\" alt=\"Irina Muradyan\" srcset=\"https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/\u053b\u0580\u056b\u0576\u0561-\u0544\u0578\u0582\u0580\u0561\u0564\u0575\u0561\u0576-\u0567\u0576\u0564\u0578\u056f\u0580\u056b\u0576\u0578\u056c\u0578\u0563\u056b\u0561\u056f\u0561\u0576-\u056e\u0561\u057c\u0561\u0575\u0578\u0582\u0569\u0575\u0561\u0576-\u0572\u0565\u056f\u0561\u057e\u0561\u0580-1-scaled-e1764836080236.avif 1580w, https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/\u053b\u0580\u056b\u0576\u0561-\u0544\u0578\u0582\u0580\u0561\u0564\u0575\u0561\u0576-\u0567\u0576\u0564\u0578\u056f\u0580\u056b\u0576\u0578\u056c\u0578\u0563\u056b\u0561\u056f\u0561\u0576-\u056e\u0561\u057c\u0561\u0575\u0578\u0582\u0569\u0575\u0561\u0576-\u0572\u0565\u056f\u0561\u057e\u0561\u0580-1-scaled-e1764836080236-359x400.avif 359w, https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/\u053b\u0580\u056b\u0576\u0561-\u0544\u0578\u0582\u0580\u0561\u0564\u0575\u0561\u0576-\u0567\u0576\u0564\u0578\u056f\u0580\u056b\u0576\u0578\u056c\u0578\u0563\u056b\u0561\u056f\u0561\u0576-\u056e\u0561\u057c\u0561\u0575\u0578\u0582\u0569\u0575\u0561\u0576-\u0572\u0565\u056f\u0561\u057e\u0561\u0580-1-scaled-e1764836080236-717x800.avif 717w, https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/\u053b\u0580\u056b\u0576\u0561-\u0544\u0578\u0582\u0580\u0561\u0564\u0575\u0561\u0576-\u0567\u0576\u0564\u0578\u056f\u0580\u056b\u0576\u0578\u056c\u0578\u0563\u056b\u0561\u056f\u0561\u0576-\u056e\u0561\u057c\u0561\u0575\u0578\u0582\u0569\u0575\u0561\u0576-\u0572\u0565\u056f\u0561\u057e\u0561\u0580-1-scaled-e1764836080236-768x856.avif 768w, https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/\u053b\u0580\u056b\u0576\u0561-\u0544\u0578\u0582\u0580\u0561\u0564\u0575\u0561\u0576-\u0567\u0576\u0564\u0578\u056f\u0580\u056b\u0576\u0578\u056c\u0578\u0563\u056b\u0561\u056f\u0561\u0576-\u056e\u0561\u057c\u0561\u0575\u0578\u0582\u0569\u0575\u0561\u0576-\u0572\u0565\u056f\u0561\u057e\u0561\u0580-1-scaled-e1764836080236-1377x1536.avif 1377w\" sizes=\"auto, (max-width: 1580px) 100vw, 1580px\" data-has-transparency=\"false\" data-dominant-color=\"b2a896\" style=\"--dominant-color: #b2a896;\" \/>                         <\/div>\n          <\/div>\n         <\/a>\n          <div class=\"box-text text-center is-small\" style=\"padding:10px 10px 10px 10px;\">\n                <div class=\"box-text-inner\">\n                  <h4 class=\"uppercase\">\n                    <span class=\"person-name\">irina muradyan<\/span><br\/>\n                    <span class=\"person-title is-small thin-font op-7\">\n                      head of endocrinology service, endocrinologist, pediatric endocrinologist                    <\/span>\n                  <\/h4>\n\t\t\t\t\t<div class=\"social-icons follow-icons\" ><a href=\"https:\/\/www.facebook.com\/IraMur\" target=\"_blank\" data-label=\"Facebook\" class=\"icon button circle is-outline tooltip facebook\" title=\"Follow on Facebook\" aria-label=\"Follow on Facebook\" rel=\"noopener nofollow\"><i class=\"icon-facebook\" aria-hidden=\"true\"><\/i><\/a><a href=\"https:\/\/www.instagram.com\/iramour\/\" target=\"_blank\" data-label=\"Instagram\" class=\"icon button circle is-outline tooltip instagram\" title=\"Follow on Instagram\" aria-label=\"Follow on Instagram\" rel=\"noopener nofollow\"><i class=\"icon-instagram\" aria-hidden=\"true\"><\/i><\/a><\/div>\n\n\n                <\/div>\n          <\/div>\n    <\/div>\n\n\t\n    \n\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1713580973\" class=\"col medium-4 small-6 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\n    <div class=\"box has-hover has-hover box-default box-text-bottom\" >\n\n         <a href=\"https:\/\/gastroclinic.am\/en\/ourstaff\/agnesa-avetikyan\/\" >         <div class=\"box-image \" >\n           <div class=\"box-image-inner image-cover\" style=\"border-radius:10%;padding-top:100%;\">\n              <img loading=\"lazy\" decoding=\"async\" width=\"1276\" height=\"1527\" src=\"https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/MG_5131-scaled-e1766607148295.avif\" class=\"attachment- size- not-transparent\" alt=\"\u0531\u0563\u0576\u0565\u057d\u0561 \u0531\u057e\u0565\u057f\u056b\u0584\u0575\u0561\u0576 Agnesa Avetikyan \u0410\u0433\u043d\u0435\u0441\u0430 \u0410\u0432\u0435\u0442\u0438\u043a\u044f\u043d\" srcset=\"https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/MG_5131-scaled-e1766607148295.avif 1276w, https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/MG_5131-scaled-e1766607148295-334x400.avif 334w, https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/MG_5131-scaled-e1766607148295-669x800.avif 669w, https:\/\/gastroclinic.am\/wp-content\/uploads\/2025\/12\/MG_5131-scaled-e1766607148295-768x919.avif 768w\" sizes=\"auto, (max-width: 1276px) 100vw, 1276px\" data-has-transparency=\"false\" data-dominant-color=\"c3c7c2\" style=\"--dominant-color: #c3c7c2;\" \/>                         <\/div>\n          <\/div>\n         <\/a>\n          <div class=\"box-text text-center is-small\" style=\"padding:10px 10px 10px 10px;\">\n                <div class=\"box-text-inner\">\n                  <h4 class=\"uppercase\">\n                    <span class=\"person-name\">agnesa avetikyan<\/span><br\/>\n                    <span class=\"person-title is-small thin-font op-7\">\n                      endocrinologist                    <\/span>\n                  <\/h4>\n\t\t\t\t\t\n\n\n                <\/div>\n          <\/div>\n    <\/div>\n\n\t\n    \n\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n\t<div id=\"col-1013666853\" class=\"col medium-4 small-6 large-4\"  >\n\t\t\t\t<div class=\"col-inner\"  >\n\t\t\t\n\t\t\t\n\n    <div class=\"box has-hover has-hover box-default box-text-bottom\" >\n\n         <a href=\"https:\/\/gastroclinic.am\/en\/ourstaff\/anna-khachatryan\/\" >         <div class=\"box-image \" >\n           <div class=\"box-image-inner image-cover\" style=\"border-radius:10%;padding-top:100%;\">\n              <img loading=\"lazy\" decoding=\"async\" width=\"1333\" height=\"1333\" src=\"https:\/\/gastroclinic.am\/wp-content\/uploads\/2026\/02\/nk4.avif\" class=\"attachment- size- has-transparency\" alt=\"\u0531\u0576\u0576\u0561 \u053d\u0561\u0579\u0561\u057f\u0580\u0575\u0561\u0576 Anna Khachatryan \u0410\u043d\u043d\u0430 \u0425\u0430\u0447\u0430\u0442\u0440\u044f\u043d\" srcset=\"https:\/\/gastroclinic.am\/wp-content\/uploads\/2026\/02\/nk4.avif 1333w, 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             <\/div>\n          <\/div>\n    <\/div>\n\n\t\n    \n\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\n\t\n\n<\/div>\n\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":8320,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[207],"tags":[],"class_list":["post-8321","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-endocrinology"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ozempic: contraindications and effectiveness | Gastro Health Center<\/title>\n<meta name=\"description\" content=\"Ozempic (semaglutide) for diabetes and obesity: mechanism of action, weight loss, risks and contraindications. 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